The Role of LONP1 in mitochondrial DNA maintenance

I received my Master degree in Cell Physiology from Charles University in Prague, the Czech Republic. I worked on my diploma thesis in the Institute of Physiology, Czech Academy of Sciences, where I studied the MLQ protein (also MP68 or 6.8 kDa proteolipid), which is a small membrane subunit of F1FO-ATP synthase. Little is known about this subunit because there are no homologues known in bacteria or yeasts and it was just recently identified as a part of mammalian ATP synthase.

Given the opportunity to be a REMIX felllow I am very excited to further investigate mitochondrial complexity. I will study the role of LONP1, a conserved AAA+ protease, in the mammalian mitochondria. I am looking forward to be a part of this international network for the next three years.