The Young Mito Investigator Symposium will be held as an online event on 15-17 September 2021.
The event consists of three afternoon sessions with presentations by young mitochondrial researchers and one Round Table Discussion on “Research in times of COVID-19”.
Register in advance for this meeting:
Day 01, Wednesday 15 September 2021, 13:00 - 16:45
Day 02, Thursday 16 September 2021, 13:00 - 17:00
Day 03, Friday 17 September 2021, 13:00 - 16:45
After registering, you will receive a confirmation email containing information about joining the meeting.
| Day 1, Wednesday 15 September 2021, 13:00 - 16:45 | ||
|---|---|---|
| 13:00 - 13:15 | Nora Voegtle | Opening remarks |
| Session 1: Mitochondrial protein import and biogensis | ||
| Chair: Daiana Moretti | ||
| 13:15 - 13:30 | Vinzent Schulz | Human mitochondrial ferredoxins 1 and 2 perform different biosynthetic functions |
| 13:30 - 13:45 | Ana Kalichava | Ultrastructure expansion microscopy in Trypanosoma bruce |
| 13:45 - 14:00 | Yury Bykov | Mitochondrial ribosomal proteins developed unconventional mitochondrial targeting signals due to structural constraints |
| 14:00 - 14:15 | Ana Sierra | Structural heterogeneity of the respiratory chain ensures optimal OXPHOS performance |
| 14:15 - 14:45 | Coffee Break | |
| Chair: Maria Gomez-Fabra Gala | ||
| 14:45 - 15:00 | Christin Albus | Investigating sub-mitochondrial localisation of translation machinery components |
| 15:00 - 15:15 | Meichel Herrade | Peculiar post-transcriptional modification of Chlamydomonas reinhardtii mitochondrial mRNAs |
| 15:15 - 15:30 | Ross Eaglesfield | Unconventional protein import pathways for dually localised proteins present in the intermembrane space |
| 15:30 - 16:00 | Coffee Break | |
| Session 2: Mitochondria in infection, inflammation and immunity | ||
| Chair: Matthijs Hermeling | ||
| 16:00 - 16:15 | Manuel M. Gomez de las Heras | Mitochondrial T cell dysfunction accelerates intestinal ageing |
| 16:15 - 16:30 | Hanna Salmonowicz | Sub-lethal apoptotic stress enables mtDNA release and drives the senescence-associated secretory phenotype |
| 16:30 - 16:45 | Andreas Jenner | Direct interaction with DRP1 activates BAX and induces apoptosis |
| Day 2, Thursday 16 September 2021, 13:00 - 17:00 | ||
|---|---|---|
| Session 2 (continued): Mitochondria in infection, inflammation and immunity | ||
| Chair: Tania Mêdeiros | ||
| 13:00 - 13:15 | Pankaj Deo | Bacterial outer membrane vesicles induce mitochondrial dysfunction and intrinsic apoptosis |
| 13:15 - 13:30 | Lena Kraemer | The Proteasome: Friend or Foe of Mitchondrial Protein Import? |
| 13:30 - 13:45 | Anna Smith | The impact of age-associated mitochondrial alterations in intestinal tumour development |
| 13:45 - 14:00 | Carolina García-Poyatos | Homo-dimerization of the mitochondrial complex IV and its role in muscle biology and regeneration |
| 14:00 - 14:30 | Round Table Discussion, Research abroad: opportunities and challenges, Lena Pernas | |
| 14:30 - 15:00 | Coffee Break | |
| Session 3: Mitochondrial dynamics and quality control | ||
| Chair: Cansu Kücükköse | ||
| 15:00 - 15:15 | Tiago Branco-Fonseca | A hypomorphic mouse model identified Fis1 as required protein for mitochondrial ultrastructure and function |
| 15:15 - 15:30 | Sebastien Leterme | Lipid transport to mitochondria during plant adaptation to phosphate starvation |
| 15:30 - 15:45 | Victoria Hewitt | Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy |
| 15:45 - 16:15 | Coffee Break | |
| 16:15 - 16:30 | Tim König | Mechanisms of MDV biogenesis: MIRO1/2 and DRP1 mediate removal of assembled protein complexes |
| 16:30 - 16:45 | Katherine Labbe | The modified mitochondrial outer membrane carrier MTCH2 regulates mitochondrial fusion in response to lipogenesis |
| 16:45 - 17:00 | Jake Winter | Co-deletion of ATAD1 with PTEN primes cells for BIM-mediated apoptosis |
| Day 3, Friday 17 September 2021, 13:00 - 16:45 | ||
|---|---|---|
| Session 3 (continued): Mitchondrial dynamics and quality control | ||
| Chair: Harshita Kaul | ||
| 13:00 - 13:15 | Caroline Dewar | Deciphering the mitochondrial quality control mechanism in the parasite Trypanosoma brucei |
| 13:15 - 13:30 | Minji Kim | Maintenance of proteostasis by mitochondrial stress response |
| 13:30 - 13:45 | Jessica Spineli | Leveraging mass spectrometry to uncover mitochondrial adaptations to hypoxia exposure |
| 13:45 - 14:15 | Coffee Break | |
| Session 4: Mitochondria in metabolic signalling and control of metabolism | ||
| Chair: Soni Deshawal | ||
| 14:15 - 14:30 | Vasili Mavridou | Mapping the substrate binding site of the mitochondrial ADP/ATP carrier |
| 14:30 - 14:45 | Chrysanthi Moschandrea | Mitochondrial OXPHOS regulates dietary lipid transport in enterocytes |
| 14:45 - 15:00 | Michela Carraro | F-ATP synthase mutagenesis and its implication on formation and regulation of the permeability transition pore |
| 15:00 - 15:15 | Greg McElroy | Reduced expression of mitochondrial complex I subunit NDUFS2 does not impact healthspan in mice |
| 15:15 - 15:45 | Coffee Break | |
| Chair: Hien Rozsivalova | ||
| 15:45 - 16:00 | Corvin Walter | Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery |
| 16:00 - 16:15 | Bruna Garcia Martins | A role for mitochondria in the regulation of cholesterol biosynthesis |
| 16:15 - 16:30 | Yilin Kang | Mutant mitochondrial DNA polymerase impairs acute antiviral immunity |
| 16:30 - 16:45 | Aleksandra Trifunovic | Closing Remarks |